Bioactive Constituents from the Twigs of Sonneratia alba


  • Kanchuree CHAIYADEJ Center for Scientific and Technological Equipment, Walailak University, Thasala, Nakhon Si Thammarat 80161
  • Hathaichanok WONGTHAP School of Science, Walailak University, Thasala, Nakhon Si Thammarat 80161
  • Surasi VADHANAVIKIT School of Allied Health Sciences and Public Health, Walailak University, Thasala, Nakhon Si Thammarat 80161
  • Kan CHANTRAPROMMA School of Science, Walailak University, Thasala, Nakhon Si Thammarat 80161


Sonneratia alba, Sonneraceae, Triterpenoids, Quinone, Antimalarial, Antimycobacterial


Three pentacyclic triterpenoids: lupeol [1], oleanolic acid [2], and betulinic acid [3] were isolated from the twigs of Sonneratia alba together with 2,6-dimethoxy-p-benzoquinone [4], a mixture of stigmasterol [5] and b-sitosterol [6]. Their structures were elucidated by analyses of their 1D and 2D NMR, and their physical and spectral data were compared with those reported in the literature. Amongst these isolates, compounds [2,3] exhibit antimycobacterial activity with MIC values of 25 and 50 mg/ml respectively. In addition, compound [4] exhibited antimalarial activity against P. falciparum with an IC50 value of 3.08 mg/ml.


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How to Cite

CHAIYADEJ, K., WONGTHAP, H., VADHANAVIKIT, S., & CHANTRAPROMMA, K. (2011). Bioactive Constituents from the Twigs of Sonneratia alba. Walailak Journal of Science and Technology (WJST), 1(1), 15–22. Retrieved from



Research Article