TY - JOUR AU - SHARMIN, Sanjida AU - JHUMA, Rabeya Gazi AU - ISLAM, Sanjida AU - KHATUN, Riniara PY - 2021/08/13 Y2 - 2024/03/29 TI - Anti-inflammatory and Anti-arthritic Potentials of Maesa Montana Roots JF - Walailak Journal of Science and Technology (WJST) JA - Walailak J Sci & Tech VL - 18 IS - 16 SE - Research Article DO - 10.48048/wjst.2021.9564 UR - https://wjst.wu.ac.th/index.php/wjst/article/view/9564 SP - Article 9564 (6 pages) AB - <p><em>Maesa Montana</em> is a flowering plant of the Myrsinaceae family, which is locally known as ramjani. The current study aimed to evaluate the <em>in-vitro</em> anti-arthritic and anti-inflammatory activities of the root extract of this plant. The anti-inflammatory performances were measured by the hindrance of egg white denaturation, and anti-arthritic activity was investigated by Bovine serum protein. In the anti-inflammatory activity test, the methanolic root extract of this plant showed 69.29 ± 1.19 % of inhibition at a concentration of 1000 µg/mL and standard drug exhibited 90.11 ± 1.45 % of inhibition at the same concentration. Furthermore, in the anti-arthritic activity test, the extract demonstrated 68.18 ± 1.34 % of inhibition at a concentration of 1000 µg/mL whereas the standard diclofenac drug showed 90.65 ± 1.19 % of inhibition at the same concentration. These results revealed that the root extract of this plant possesses significant anti-arthritic and anti-inflammatory activities based on the inhibition of BSA and protein denaturation.</p><p><strong>HIGHLIGHTS</strong></p><ul><li>Methanol soluble compounds extraction from the roots of <em>Maesa Montana</em></li><li>Anti-inflammatory activity determination using egg albumin</li><li>Anti-arthritic activity measurement using bovine serum albumin</li></ul><p><strong>GRAPHICAL ABSTRACT</strong><br /><img src="https://wjst.wu.ac.th/public/site/images/admin/9564-grafical-abstract.jpg" alt="" width="960" height="720" /></p> ER -