Synergism of Zinc Oxide Nano-Powder with Active Compound from Turmeric and Lemongrass as Bacterial Inhibitor


  • Gee Een LAU Material Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Selangor, Malaysia
  • Che Azurahanim CHE ABDULLAH Department of Physics, Faculty of Science, Universiti Putra Malaysia, Selangor, Malaysia
  • Mohd Sabri MOHD GHAZALI Department of Nano Physics, Universiti Malaysia Terengganu, Terenggganu, Malaysia
  • Muhamad Syazlie CHE IBRAHIM Department of Biological Science, Universiti Malaysia Terengganu, Terengganu, Malaysia



Metal oxide, Green synergism, Escherichia coli, Synergism, Green product, Active Compound, Turmeric, Lemongrass, Bacterial inhibitor


Green nanoparticles are receiving great attention due to their broad fields of application. Plant extracts are promising sources, since the synergizing process is easy and cost-effective. Green synergism offers safer nanomaterials for both human health and the environment. The antimicrobial application of prepared nanoparticles is due to special capabilities at the nanoscale size. Green zinc oxide nanoparticles (ZnONPs) from lemongrass and turmeric revealed good antibacterial properties. Antibacterial active compounds were extracted from lemongrass and turmeric using methanol as a solvent. The extracts were introduced to zinc oxide solution to create synergized green ZnONPs and tested for their antibacterial properties. The samples were characterized by means of XRD, SEM, FTIR, and GC-MS. The zones of inhibition of synergized green ZnONPs were successfully measured using the disc diffusion method. The findings using gram-negative bacteria Escherichia coli. showed a higher antibacterial inhibition zone, with a diameter of 1.6 cm. The gram-positive bacteria, Staphylococcus aureus., showed low antibacterial inhibition. The addition of ZnO had positively revealed greater inhibition. Green ZnONPs synthesized using plant extracts will be further tested for various applications.


  • Green zinc oxide nanoparticles (ZnONPs) prepared from lemongrass and turmerics
  • Plant extracts are significant in reducing and stabilizing metallic ions
  • The synergism of ZnONPs was successfully prepared from plant extract active and evaluated for their antibacterial activity using Staphylococcus aureus and Escherichia coli
  • The zones of inhibition of synergized green ZnONPs measured using the disc diffusion method showed a higher antibacterial inhibition zone
  • Antibacterial activity revealed the potential applications of green synergism of ZnONPs for treatment of contaminated water, medical applications, and cosmetics



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How to Cite

LAU, G. E. ., CHE ABDULLAH, C. A., MOHD GHAZALI, M. S. ., & CHE IBRAHIM, M. S. . (2021). Synergism of Zinc Oxide Nano-Powder with Active Compound from Turmeric and Lemongrass as Bacterial Inhibitor. Walailak Journal of Science and Technology (WJST), 18(11), Article 9652 (14 pages).