Anti-inflammatory and Anti-arthritic Potentials of Maesa Montana Roots
Keywords:Maesa Montana, Anti-arthritic, Anti-inflammatory, Protein denaturation
Maesa Montana is a flowering plant of the Myrsinaceae family, which is locally known as ramjani. The current study aimed to evaluate the in-vitro anti-arthritic and anti-inflammatory activities of the root extract of this plant. The anti-inflammatory performances were measured by the hindrance of egg white denaturation, and anti-arthritic activity was investigated by Bovine serum protein. In the anti-inflammatory activity test, the methanolic root extract of this plant showed 69.29 ± 1.19 % of inhibition at a concentration of 1000 µg/mL and standard drug exhibited 90.11 ± 1.45 % of inhibition at the same concentration. Furthermore, in the anti-arthritic activity test, the extract demonstrated 68.18 ± 1.34 % of inhibition at a concentration of 1000 µg/mL whereas the standard diclofenac drug showed 90.65 ± 1.19 % of inhibition at the same concentration. These results revealed that the root extract of this plant possesses significant anti-arthritic and anti-inflammatory activities based on the inhibition of BSA and protein denaturation.
- Methanol soluble compounds extraction from the roots of Maesa Montana
- Anti-inflammatory activity determination using egg albumin
- Anti-arthritic activity measurement using bovine serum albumin
AG Atanasov, B Waltenberger, EM Pferschy-Wenzig, T Linder, C Wawrosch, P Uhrin, V Temml, L Wang, S Schwaiger, EH Heiss and JM Rollinger. Discovery and resupply of pharmacologically active plant-derived natural products: A review. Biotechnol. Adv. 2015; 33, 1582-614.
Z Morshed. 2018, Phytochemical and biological screening of methanol extract of Maesa Montana
(Myrsinaceae) leave. Bachelor Dissertation. BRAC University, Dhaka, Bangladesh.
F Firenzuoli and L Gori. Herbal medicine today: Clinical and research issues. Evidence-based Compl. Alternative Med. 2007; 4, 37-40.
The Editors of Encyclopaedia Britannica, Available at: https://www.britannica.com/science/ inflammation, assessed March 2021.
L Chen, H Deng, H Cui, J Fang, Z Zuo, J Deng, Y Li, X Wang and L Zhoa. Inflammatory responses and inflammation-associated diseases in organs. Oncotarget 2018; 9, 7204-18.
CV Tehlirian and JM Bathon. Rheumatoid arthritis. In: JH Klippel, JH Stone, LJ Crofford and PH White (Eds.). Primer on the rheumatic diseases. Springer, New York, 2010, p. 114-41.
DP Orchanian. Rheumatic diseases. In: B Atchison and DP Dirette (Eds.). Conditions in occupational therapy. Wolters Kluwer/Lippincott Williams & Wilkins, Philadelphia, 2012, p. 225.
S Sharmin, T Sifat, A Azad, A Reza, MK Islam and MA Sayeed. Preliminary phyto-pharmacological investigation of Duabanga grandiflora (Roxb. ex DC.) Walpers. Bangladesh pharmaceut. J. 2020; 23, 54-60.
Trees and Shrubs Online, Available at: https://treesandshrubsonline.org/articles/maesa/maesa-montana, accessed March 2021.
Flora of China Editorial Committee. Flora of China. China, 2018, p. 3.
SS Sakat, AR Juvekar and MN Gambhire. In-vitro antioxidant and anti-inflammatory activity of methanol extract of Oxalis corniculata Linn. Int. J. Pharm. Pharmaceut. Sci. 2010; 2, 146-55.
G Leelaprakash and SM Dass. In vitro anti-inflammatory activity of methanol extract of Enicostemma axillare. Int. J. Drug Dev. Res. 2011; 3,189-96.
S Chandra, P Dey and S Bhattacharya. Preliminary in vitro assessment of anti-inflammatory property of Mikania scandens flower extract. J. Adv. Pharm. Educ. Res. 2012; 2, 25-31.
CS Kumari, N Yasmin, MR Hussain and M Babuselvam. In vitro anti-inflammatory and anti-arthritic property of Rhizopora mucronata leaves. Int. J. Pharm. Sci. Res. 2015; 6, 482-5.
AA Kamble, ND Khan, ZH Khan, SM Mular and S Sohail. In vitro anti-arthritic activity of vitex negundo and punica granatum. Res. J. Pharm. Sci. 2017; 6, 5-7.
How to Cite
Copyright (c) 2021 Walailak University
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.