Anti-inflammatory and Anti-arthritic Potentials of Maesa Montana Roots
DOI:
https://doi.org/10.48048/wjst.2021.9564Keywords:
Maesa Montana, Anti-arthritic, Anti-inflammatory, Protein denaturationAbstract
Maesa Montana is a flowering plant of the Myrsinaceae family, which is locally known as ramjani. The current study aimed to evaluate the in-vitro anti-arthritic and anti-inflammatory activities of the root extract of this plant. The anti-inflammatory performances were measured by the hindrance of egg white denaturation, and anti-arthritic activity was investigated by Bovine serum protein. In the anti-inflammatory activity test, the methanolic root extract of this plant showed 69.29 ± 1.19 % of inhibition at a concentration of 1000 µg/mL and standard drug exhibited 90.11 ± 1.45 % of inhibition at the same concentration. Furthermore, in the anti-arthritic activity test, the extract demonstrated 68.18 ± 1.34 % of inhibition at a concentration of 1000 µg/mL whereas the standard diclofenac drug showed 90.65 ± 1.19 % of inhibition at the same concentration. These results revealed that the root extract of this plant possesses significant anti-arthritic and anti-inflammatory activities based on the inhibition of BSA and protein denaturation.
HIGHLIGHTS
- Methanol soluble compounds extraction from the roots of Maesa Montana
- Anti-inflammatory activity determination using egg albumin
- Anti-arthritic activity measurement using bovine serum albumin
GRAPHICAL ABSTRACT
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