Health-related quality of life and related factors in Thais with stable COPD



This study aims to explore the health-related quality of life (HRQL) and related factors of the southern Thai patients with stable COPD. The methodology was the cross-sectional descriptive study. The sample consists of 126 patients with COPD attending the outpatient pulmonary clinic of Thasala hospital. The patients were assessed the HRQL by the Saint George's Respiratory Questionnaire (SGRQ), age, BMI, depression, dyspnea by the Modified Medical Research Council (mMRC), exercise capacity by the 6-min walk distance (6MWD), and hospital utilization. The results found that most patients were male 84%; they had a mean of age 69.6(9.5) years, FEV1 70(9.6) % predicted, BMI 21.9(4.4) and 6MWD 259.8(97.9). The HRQL indicated moderate impairment: symptom 47.1(22.4), activity 49.7(30.3), impact 41.9(21.2) and total scores 45.1(21.7). The regression analysis shows that HRQL were the most affected by 6MWD, depression, dyspnea, and admission respectively (β = -.364, .311, .296, and .180; R2 = .501, p < .05). Thus, patients with poor exercise capacity (6MWD <350m), depression and dyspnea scored significantly higher (greater impairment) on all components of HRQL. Therefore, stable COPD patients should be motivated to exercise for promoting exercise capacity (6MWD), reducing depression for improving their HRQL.


COPD, stable, quality of life, related factors


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