Application of Biosurfactants in the Medical Field

Authors

  • Atipan SAIMMAI Faculty of Agricultural Technology, Phuket Rajabhat University, Phuket 83000, Thailand
  • Wiboon RIANSA-NGAWONG Faculty of Agro-Industry, King Mongkut's University of Technology North Bangkok, Prachinburi 25230, Thailand
  • Suppasil MANEERAT Biotechnology for Bioresource Utilization Laboratory, Department of Industrial Biotechnology, Faculty of Agro-Industry, Prince of Songkla University, Songkhla 90110, Thailand
  • Paweena DIKIT Faculty of Science and Technology, Songkla Rajabhat University, Songkhla 90000, Thailand

Keywords:

Biosurfactants, Antimicrobial, Antiviral, Anti-mycoplasma, Anti-tumor, Anti-inflammatory

Abstract

It is generally known that both chemical substances and many kinds of microorganism can be used to produce surfactants or surface-active compounds. Surfactants derived from microorganisms are called biosurfactants, or bio-surface active compounds. Recently, biosurfactants have become more interesting because of their advantages, such as less toxicity and more degradability, which cannot be found in traditional surfactants. Biosurfactant production faces some problems, such as a high cost of production. In the medical field, biosurfactants are attractive, because the products from biosurfactants can be used effectively in small amounts. This can compensate for the high cost of production. In addition, there have been many great discoveries of biosurfactants in the medical field.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

A Roy. A review on the biosurfactants: Properties, types and its applications. J. Fund. Renew. Energ. Appl. 2017; 8, 1-5.

AM Abdel-Mawgoud, F Lepine and E Deziel. Rhamnolipids: Diversity of structures, microbial origins and roles. Appl. Microbiol. Biotechnol. 2010; 86, 1323-36.

IM Banat, A Franzetti, I Gandolfi, G Bestetti, MG Martinotti, L Fracchia, TJ Smyth and R Marchant. Microbial biosurfactants production, applications and future potential. Appl. Microbiol. Biotechnol. 2010; 87, 427-44.

I Mnif and D Ghribi. Review lipopeptides biosurfactants: Mean classes and new insights for industrial, biomedical, and environmental applications. Pep. Sci. 2015; 104, 129-47.

SK Satpute, IM Banat, PK Dhakephalkar, AG Banpurkar and BA Chopade. Biosurfactants, bioemulsifiers and exopolysaccharides from marine microorganisms. Biotechnol. Adv. 2010; 28, 436-50.

T Matsuyama, T Tanikawa and Y Nakagawa. Serrawettins and Other Surfactants Produced by Serratia. In: G Soberón-Chávez (Ed.). Biosurfactants: From Genes to Applications, 2010, p. 93-120.

J Fechtner, S Cameron, YY Deeni, SM Hapca, K Kabir, IU Mohammed and AJ Spiers. Limitation of Biosurfactant Strength Produced by Bacteria. In: CR Upton (Ed.). Biosurfactants: Occurrences, Applications and Research. Nova Science Publishers, Hauppauge, NY, 2017, p. 125-48.

LL Fracchia, M Cavallo, MG Martinotti and IM Banat. Biosurfactants and bioemulsifiers biomedical and related applications-present status and future potentials. Biomed. Sci. Eng. Tech. 2012; 14, 325-70.

J Arutchelvi and M Doble. Characterization of glycolipid biosurfactant from Pseudomonas aeruginosa CPCL isolated from petroleum-contaminated soil. Lett. Appl. Microbiol. 2010; 51, 75-82.

KKS Randhawa and PKSM Rahman. Rhamnolipid biosurfactants-past, present, and future scenario of global market. Front. Microbiol. 2014; 5, 1-7.

P Biniarz, M Łukaszewicz and T Janek. Screening concepts, characterization and structural analysis of microbial-derived bioactive lipopeptides: a review. Crit. Rev. Biotechnol. 2017; 37, 393-410.

D Biria, E Maghsoudi, R Roostaazad, H Dadafarin, AS Lotfiand and MA Amoozegar. Purification and characterization of a novel biosurfactant produced by Bacillus licheniformis MS3. World J. Microbiol. Biotechnol. 2010; 26, 871-8.

LR Rodrigues and JA Teixeira. Biomedical and therapeutic applications of biosurfactants. Adv. Exp. Med. Biol. 2010; 75, 672-87.

A Franzetti, I Gandolfi, G Bestetti, TJP Smyth and IM Banat. Production and applications of trehalose lipid biosurfactants. Eur. J. Lipid. Sci. Tech. 2010; 112, 617-27.

G Seydlova and J Svobodova. Review of surfactin chemical properties and the potential biomedical applications. Cent. Eur. J. Med. 2008; 3, 122-33.

M Nitschke, SG Costa and J Contiero. Structure and applications of a rhamnolipid surfactant produced in soybean oil waste. Appl. Biochem. Biotechnol. 2010; 160, 2066-74.

SS Cameotra and RS Makkar. Recent applications of biosurfactants as biological and immunological molecules. Curr. Opin. Microbiol. 2004; 7, 262-6.

P Singh and SS Cameotra. Potential applications of microbial surfactants in biomedical sciences. Trends Biotechnol. 2004; 22, 142-6.

K Muthusamy, S Gopalakrishnan, TK Ravi and P Sivachidambaram. Biosurfactants: Properties, commercial production and application. Curr. Sci. India. 2008; 94, 736-47.

Z Shao. Trehalolipids in Biosurfactants: From Genes to Applications. Springer, Germany, 2010, p. 121-43.

SK Satpute, GR Kulkarni, AG Banpurkar, IM Banat, NS Mone, RH Patil and SS Cameotra. Biosurfactants from Lactobacilli species: Properties, challenges and potential biomedical applications. J. Basic. Micro. 2016; 56, 1140-58.

M Deleu, M Paquot and T Nylander. Effect of fengycin, a lipopeptide produced by Bacillus subtilis, on model biomembranes. Biophys. J. 2008; 94, 2667-79.

JM Bonmatin, O Laprevoteand and F Peypoux. Diversity among microbial cyclic lipopeptides: Iturins and surfactins, activity-structure relationships to design new bioactive agents. Comb. Chem. High. T. Scr. 2003; 6, 541-56.

JR Lu, XB Zhao and M Yaseen. Biomimetic amphiphiles: Biosurfactants. Curr. Opin. Colloid In. 2007; 12, 60-7.

P Das, S Mukherjee and R Sen. Antimicrobial potential of a lipopeptide biosurfactant derived from a marine Bacillus circulans. J. Appl. Microbiol. 2008; 104, 1675-84.

X Huang, J Suo and Y Cui. Optimization of antimicrobial activity of surfactin and polylysine against Salmonella enteritidis in milk evaluated by a response surface methodology. Foodborne Pathog. Dis. 2011; 8, 439-43.

M Ongena, E Jourdan, A Adam, M Paquot, A Brans, B Joris, JL Arpigny and P Thonart. Surfactin and fengycin lipopeptides of Bacillus subtilis as elicitors of induced systemic resistance in plants. Environ. Microbiol. 2007; 9, 1084-90.

M Ongena and P Jacques. Bacillus lipopeptides: versatile weapons for plant disease biocontrol. Trends Microbiol. 2008; 16, 115-24.

X Huang, Z Lu, X Bie, F Lu, H Zhao and S Yang. Optimization of inactivation of endospores of Bacillus cereus by antimicrobial lipopeptides from Bacillus subtilis fmbj strains using a response surface method. Appl. Microbiol. Biotechnol. 2007; 74, 454-61.

N Naruse, O Tenmyo, S Kobaru, H Kamei, T Miyaki, M Konishi and T Oki. Pumilacidin, a complex of new antiviral antibiotics: Production, isolation, chemical properties, structure and biological activity. J. Antibiot. 1990; 43, 267-80.

D Landman, C Georgescu, DA Martin and J Quale. Polymyxins revisited. Clin. Microbiol. Rev. 2008; 21, 449-65.

M Fiore, AE Maraolo, I Gentile, G Borgia, S Leone, P Sansone, MB Passavanti, C Aurilio and MC Pace. Nosocomial spontaneous bacterial peritonitis antibiotic treatment in the era of multi-drug resistance pathogens: A systematic review. World J. Gastroenterol. 2017; 23, 4654-60.

Y Liu, S Ding, R Dietrich, E Martlbauer and K Zhu. Corrigendum: A biosurfactant-inspired heptapeptide with improved specificity to kill MRSA. Angew. Chem. Int. Ed. Engl. 2017; 56, 1486-90.

HS Saini, BE Barragan-Huerta, A Lebron-Paler, JE Pemberton, RR Vazquez, AM Burns, MT Marron, CJ Seliga, AA Gunatilaka and RM Maier. Efficient purification of the biosurfactant viscosin from Pseudomonas libanensis strain M9-3 and its physicochemical and biological properties. J. Nat. Prod. 2008; 71, 1011-5.

I Mnif and D Ghribi. Glycolipid biosurfactants: Main properties and potential applications in agriculture and food industry. J. Sci. Food. Agric. 2016; 96, 4310-20.

M Benincasa, A Abalos, I Oliveira and A Manresa. Chemical structure, surface properties and biological activities of the biosurfactant produced by Pseudomonas aeruginosa LBI from soapstock. A. Van. Leeuw. 2004; 85, 1-8.

D Kitamoto, H Yanagishita, T Shinbo, T Nakane, C Kamisawa and T Nakahara. Surface active properties and antimicrobial activities of mannosylerythritol lipids as biosurfactants produced by Candida antarctica. J. Biotechnol. 1993; 29, 91-6.

A Fariq and A Saeed. Production and biomedical applications of probiotic biosurfactants. Curr. Microbiol. 2016; 72, 489-95.

B Mimee, R Pelletier and RR Belanger. In vitro antibacterial activity and antifungal mode of action of flocculosin, a membrane-active cellobiose lipid. J. Appl. Microbiol. 2009; 107, 989-96.

X Huang, Z Lu, H Zhao, X Bie, FX Lu and S Yang. Antiviral activity of antimicrobial lipopeptide from Bacillus subtilis fmbj against pseudorabies virus, porcine parvovirus, newcastle disease virus and infectious bursal disease virus in vitro. Int. J. Pept. Res. Ther. 2006; 12, 373-7.

D Vollenbroich, M Ozel, J Vater, RM Kamp and G Pauli. Mechanism of inactivation of enveloped viruses by the biosurfactant surfactin from Bacillus subtilis. Biol. 1997; 25, 289-97.

V Shah, GF Doncel, T Seyoum, KM Eaton, I Zalenskaya, R Hagver, A Azim and R Gross. Sophorolipids, microbial glycolipids with anti-human immunodeficiency virus and sperm-immobilizing activities. Antimicrob. Agents Chemother. 2005; 49, 4093-100.

M Remichkova, D Galabova, I Roeva, E Karpenko, A Shulgaand, AS Galabov. Anti-herpesvirus activities of Pseudomonas sp. S-17 rhamnolipid and its complex with alginate. Z. Naturforsch C 2008; 63, 75-81.

D Vollenbroich, G Pauli, M Ozel and J Vater. Antimycoplasma properties and application in cell culture of surfactin, a lipopeptide antibiotic from Bacillus subtilis. Appl. Environ. Microbiol. 1997; 63, 44-9.

A Kumar, A Ali and LK Yerneni. Effectiveness of a mycoplasma elimination reagent on a mycoplasma-contaminated hybridoma cell line. Hybridoma (Larchmt) 2007; 26, 104-6.

YR Chung, CH Kim, I Hwang and J Chun. Paenibacillus koreensis sp. nov., a new species that produces an iturin-like antifungal compound. Int. Syst. Evol. Microbiol. 2000; 50, 1495-500.

P Vatsa, L Sanchez, C Clement, F Baillieul and S Dorey. Rhamnolipid biosurfactants as new players in animal and plant defense against microbes. Int. J. Mol Sci. 2010; 11, 5095-108.

H Osada. Bioprobe for investigating mammalian cell cycles control. J. Antibiot. 1998; 51, 973-82.

XH Cao, AH Wang, CL Wang, DZ Mao, MF Lu, YQ Cui and RZ Jiao. Surfactin induces apoptosis in human breast cancer MCF-7 cells through a ROS/JNK-mediated mitochondrial/caspase pathway. Chem. Biol. Interact. 2010; 183, 357-62.

XH Cao, SS Zhao, DY Liu, Z Wang, LL Niu, LH Houand and CL Wang. ROS-Ca2+ is associated with mitochondria permeability transition pore involved in surfactin induced MCF-7 cells apoptosis. Chem. Biol. Interact. 2011; 190, 16-27.

BR Singh, BN Singh, W Khan, HB Singh and AH Naqvi. ROS-mediated apoptotic cell death in prostate cancer LNCaP cells induced by biosurfactant stabilized CdS quantum dots. Biomater. 2012; 33, 5753-67.

C Sivapathasekaran, P Das, S Mukherjee, J Saravanakumar, M Maland and R Sen. Marine bacterium derived lipopeptides: characterization and cytotoxic activity against cancer cell lines. Int. J. Pept. Res. Ther. 2010; 16, 215-22.

SE Byeon, YG Lee, BH Kim, T Shen, SY Lee, HJ Park, SC Park, MH Rhee and JY Cho. Surfactin blocks NO production in lipopolysaccharide-activated macrophages by inhibiting NF-κB activation. J. Microbiol. Biotechnol. 2008; 18, 1984-89.

R Selvam, P Maheswari, P Kavitha, M Ravichandran, B Sas and CN Ramchand. Effect of Bacillus subtilis PB6, a natural probiotic on colon mucosal inflammation and plasma cytokines levels in inflammatory bowel disease. Indian J. Biochem. Biophys. 2009; 46, 79-85.

JS Tang, F Zhao, H Gao, Y Dai, ZH Yao, K Hong, J Li, WC Ye and XS Yao. Characterization and online detection of surfactin isomers based on HPLC-MSn analyses and their inhibitory effects on the overproduction of nitric oxide and the release of TNF-α and IL-6 in LPS-induced macrophages. Mar. Drugs. 2010; 8, 2605-18.

SY Park, YH Kim, EK Kim, EY Ryu and SJ Lee. Heme oxygenase-1 signals are involved in preferential inhibition of pro-inflammatory cytokine release by surfactin in cells activated with Porphyromonas gingivalis lipopolysaccharide. Chem. Biol. Interact. 2010; 188, 437-45.

SY Park and Y Kim. Surfactin inhibits immunostimulatory function of macrophages through blocking NK-κB, MAPK and Akt pathway. Int. Immunopharmacol. 2009; 9, 886-93.

MS Kuyukina, IB Ivshina, SV Gein, TA Baeva and VA Chereshnev. In vitro immunomodulating activity of biosurfactant glycolipid complex from Rhodococcus ruber. Bull. Exp. Biol. Med. 2007; 144, 326-30.

Y Han, X Huang, M Cao and Y Wang. Micellization of surfactin and its effect on the aggregate conformation of amyloid beta (1-40). J. Phys. Chem. B 2008; 112, 15195-201.

O Bouffioux, A Berquand, M Eeman, M Paquot, YF Dufrene, R Brasseur and M Deleu. Molecular organization of surfactin-phospholipid monolayers: Effect of phospholipid chain length and polar head. Biochim. Biophys. Acta Biomembr. 2007; 1768, 1758-68.

R Brasseur, N Braun, KE Kirat, M Deleu, MP Mingeot-Leclercq and YF Dufrene. The biologically important surfactin lipopeptide induces nanoripples in supported lipid bilayers. Langmuir 2007; 23, 9769-72.

G Francius, S Dufour, M Deleu, M Paquot, MP Mingeot-Leclercq and YF Dufrene. Nanoscale membrane activity of surfactins: Influence of geometry, charge and hydrophobicity. Biochim. Biophys. Acta 2008; 1778, 2058-68.

M Eeman, G Francius, YF Dufrene, K Nott, M Paquot and M Deleu. Effect of cholesterol and fatty acids on the molecular interactions of fengycin with stratum corneum mimicking lipid monolayers. Langmuir 2009; 25, 3029-39.

T Morita, E Ito, HK Kitamoto, K Takegawa, T Fukuoka, T Imura and D Kitamoto. Identification of the gene PaEMT1 for biosynthesis of mannosylerythritol lipids in the basidiomycetous yeast Pseudozyma antarctica. Yeast 2010; 27, 905-17.

S Yamamoto, T Fukuoka, T Imura, T Morita, S Yanagidani, D Kitamoto and M Kitagawa. Production of a novel mannosylerythritol lipid containing a hydroxy fatty acid from castor oil by Pseudozyma tsukubaensis. J. Oleo. Sci. 2013; 62, 381-9.

A Zaragoza, FJ Aranda, MJ Espuny, JA Teruel, A Marques, A Manresa and A Ortiz. Mechanism of membrane permeabilization by a bacterial trehalose lipid biosurfactant produced by Rhodococcus sp. Langmuir 2009; 25, 7892-8.

M Sanchez, FJ Aranda, JA Teruel, MJ Espuny, A Marques, A Manresa and A Ortiz. Permeabilization of biological and artificial membranes by a bacterial dirhamnolipid produced by Pseudomonas aeruginosa. J. Colloid. Interface. Sci. 2010; 341, 240-7.

T Schneider, K Gries, M Josten, I Wiedemann, S Pelzer, H Labischinski and HG Sahl. The lipopeptide antibiotic Friulimicin B inhibits cell wall biosynthesis through complex formation with bactoprenol phosphate. Antimicrob. Agents Chemother. 2009; 53, 1610-8.

K Jenny, O Kappeli and A Fietcher. Biosurfactants from Bacillus licheniformis: Structural analysis and characterization. Appl. Microbiol. Biotechnol. 1991; 36, 5-13.

N Naruse, O Tenmyo, S Kobaru, H Kamei, T Miyaki, M Konishi and T Oki. Pumilacidin, a complex of new antiviral antibiotics: Production, isolation, chemical properties, structure and biological activity. J. Antibiot. 1990; 43, 267-80.

AS Nerurkar. Structural and molecular characteristics of lichenysin and its relationship with surface activity. Adv. Exp. Med. Biol. 2010; 672, 304-15.

A Kumar, S Saini, V Wray, M Nimtz, A Prakash and BN Johri. Characterization of an antifungal compound produced by Bacillus sp. strain A(5) F that inhibits Sclerotinia sclerotiorum. J. Basic. Microbiol. 2012; 52, 670-8.

D Kitamoto, H Yanagishita, T Shinbo, T Nakane, C Kamisawa and T Nakahara. Surface active properties and antimicrobial activities of mannosylerythritol lipids as biosurfactants produced by Candida antarctica. Appl. Microbiol. Biot. 1993; 29, 91-6.

M Velraeds, HCV der Mei, G Reid and HJ Busscher. Inibition of initial adhesion of uropathogenic enterococcus faecalis to solid substrata by an adsorbed biosurfactant layer from Lactobacillus acidophilus. Urology 1997; 49, 790-4.

LR Rodrigues, HCV der Mei, J Teixeira and R Oliveira. Influence of biosurfactants from probiotic bacteria on formation of biofilms on voice prostheses. Appl. Environ. Microbiol. 2004; 70, 4408-10.

N Christova, B Tuleva, A Kril, M Georgieva, S Konstantinov, I Terziyski, B Nikolova and I Stoineva. Chemical Structure and In Vitro Antitumor Activity of Rhamnolipids from Pseudomonas aeruginosa BN10. Appl. Biochem. Biotechnol. 2013; 170, 676-89.

K Reder-Christ, Y Schmidt, M Dorr, HG Sahl, M Josten, JM Raaijmakers, H Gross and G Bendas. Model membrane studies for characterization of different antibiotic activities of lipopeptides from Pseudomonas. Biochim. Biophys. Acta 2012; 1818, 566-73.

H Gross, JE Loper. Genomics of secondary metabolite production by Pseudomonas spp. Nat. Prod. Rep. 2009; 26, 1408-46.

A Zaragoza, FJ Aranda, MJ Espuny, JA Teruel, A Marques, A Manresa and A Ortiz. Hemolytic Activity of a Bacterial Trehalose Lipid Biosurfactant Produced by Rhodococcus sp.: Evidence for a Colloid-Osmotic Mechanism. Langmuir 2010; 26, 8567-72.

JM Miro, JM Entenza, AD Rio, M Velasco, X Castaneda, CG de la Maria, M Giddey, Y Armero, JM Pericàs, C Cervera, CA Mestres, M Almela, C Falces, F Marco, P Moreillon and A Moreno. High-dose daptomycin plus fosfomycin was safe and effective in treating methicillin-susceptible (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) endocarditis: From bench to bedside. Antimicrob. Agents Chemother. 2012; 56, 4511-5.

Y Uchida, R Tsuchiya, M Chino, J Hirano and T Tabuchi. Extracellular accumulation of mono and di succinyl trehalose lipids by a strain of Rodococcus erythropolis grown on n-alkanes. Agric. Biol. Chem. 1989; 53, 757-63.

D Vollenbroich, G Pauli, M Ozel and J Vater. Antimycoplasma properties and application in cell culture of surfactin, a lipopeptide antibiotic from Bacillus subtilis. Appl. Environ. Microbiol. 1997; 63, 44-49.

D Vollenbroich, M Ozel, J Vater, RM Kamp and G Pauli. Mechanism of inactivation of enveloped viruses by the biosurfactant surfactin from Bacillus subtilis. Biologicals 1997; 25, 289-97.

K Kim, SY Jung, DK Lee, JK Jung, JK Park, DK Kim and CH Lee. Suppression of inflammatory responses by surfactin, a selective inhibitor of platelet cytosolic phospholipase A2. Biochem. Pharmacol. 1998; 55, 975-85.

K Muthusamy, S Gopalakrishnan, TK Ravi and P Sivachidambaram. Biosurfactants: Properties, commercial production and application. Curr. Sci. India. 2008; 94, 736-74.

F Peypoux, JM Bonmatin, H Labbe, I Grangemard, BC Das, M Ptak, J Wallach and G Michel. [Ala4]surfactin, a novel isoform from Bacillus subtilis studied by mass and NMR spectroscopies. Eur. J. Biochem. 1994; 224, 89-96.

F Ahimou, P Jacques and M Deleu. Surfactin and iturin a effects on Bacillus subtilis surface hydrophobicity. Enzyme Microb. Tech. 2001; 27, 749-54.

VMF Lima, VLD Bonato, KM Lima, SAD Santos, RRD Santos, EDC Gonçalves, LH Faccioli, IT Brandão, JM Rodrigues-Junior and CL Silva. Role of trehalose dimycolate in recruitment of cells and modulation of production of cytokines and NO in tuberculosis. Infect. Immun. 2001; 69: 5305-12.

B Tuleva, N Christova, R Cohen, D Antonova, T Todorov and I Stoineva. Isolation and characterization of trehalose tetraester biosurfactants from a soil strain Micrococcus luteus BN56. Process. Biochem. 2009; 44, 135-41.

T Morita, Y Ogura, M Takashima, N Hirose, T Fukuoka, T Imura, Y Kondo and D Kitamoto. Isolation of Pseudozyma churashimaensis sp. nov., a novel ustilaginomycetous yeast species as a producer of glycolipid biosurfactants, mannosylerythritol lipids. J. Biosci. Bioeng. 2011; 112, 137-44.

LJ Cortes and NJ Russi. Echinocandins. Rev Chilena Infectol. 2011; 28, 529-36.

LR Rodrigues, HC Van der Mei, IM Banat, J Teixeira and R Oliveira. Inhibition of microbial adhesion to silicone rubber treated with biosurfactant from Streptococcus thermophilus A. FEMS. Immunol. Med. Microbiol. 2006; 46, 107-12.

T Morita, Y Ishibashi, N Hirose, K Wada, M Takahashi, T Fukuoka, T Imura, H Sakai, M Abe and D Kitamoto. Production and characterization of a glycolipid biosurfactant, mannosylerythritol lipid B, from sugarcane juice by Ustilago scitaminea NBRC 32730. Biosci. Biotechnol. Biochem. 2011; 75, 1371-6.

Downloads

Published

2019-06-20

How to Cite

SAIMMAI, A. ., RIANSA-NGAWONG, W. ., MANEERAT, S. ., & DIKIT, P. . (2019). Application of Biosurfactants in the Medical Field. Walailak Journal of Science and Technology (WJST), 17(2), 154-166. Retrieved from http://wjst.wu.ac.th/index.php/wjst/article/view/4748