Association of Biometric Traits with Growth Hormone Gene Diversity in Raini Cashmere Goats

Authors

  • Fatemeh Gholamhoseinzadeh GOOKI Department of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman
  • Mohammadreza MOHAMMADABADI Department of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman http://orcid.org/0000-0002-1268-3043
  • Masoud Asadi FOZI Department of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman
  • Mohammad SOFLAEI Kerman Agricultural and Natural Resources Research and Education Center, AREEO, Kerman

DOI:

https://doi.org/10.48048/wjst.2019.3791

Keywords:

PCR-RFLP, Raini Cashmere goat, birth weight, fleece weight, birth type

Abstract

In recent years, the important effects of growth hormone on a broad variety of physiological parameters, such as lactation, reproduction, growth, and metabolism, have attracted many researchers' attentions. To detect GH gene polymorphism and its association with the biometric traits of Raini Cashmere goats, 300 animals were selected and the animals’ genotype was determined using PCR-RFLP. Two different genotypes (AA and AB) were observed in exons 2 and 3 within the goat GH gene. The genotype frequencies for AA, AB, and BB were 0.15, 0.85, and 0, and frequencies of the A and B alleles were 0.575 and 0.425, respectively. The number of observed alleles, number of effective alleles, expected heterozygosity, observed heterozygosity, mean of heterozygosity, expected homozygosity, observed homozygosity, Nei’s index, Shannon’s index, and Fixation index (Fis) were 2, 1.96, 0.49, 0.85, 0.49, 0.51, 0.15, 0.49, 0.69, and -0.74, respectively. Birth type had a significant effect on the Chest height to earth (T26) trait (P-value = 0.032304). Furthermore, a significant effect of age on some biometric traits were observed in this study. The frequency of the AB genotype for most of the traits were higher in comparison to the AA genotype, although some traits did not show a significant effect, which might be explained by the heterosis phenomenon. According to the results, it can be concluded that allele A of growth hormone is a suitable allele for the THH (Toe height of hand hoof), THF (Toe height of foot hoof), HHF (Heel height of foot hoof), and CHE (Chest height to earth) traits, and allele B is a worthy allele for the NI (Nasal interval), LCI (Lip corner interval), NL (Neck length), CC (Chest circumference), AC (Abdominal circumference), LLF (Leg length of foot), WHC (Wither height to under the chest), and DAD (Dorsal angle distance of scapula to Hänsch point) traits. Therefore, better results in the breeding programs for these traits can be achieved from this information, along with other phenotypic records.

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Author Biography

Mohammadreza MOHAMMADABADI, Department of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman

Department of Animal Science

References

S Shamsalddini, MR Mohammadabadi and AK Esmailizadeh. Polymorphism of the prolactin gene and its effect on fiber traits in goat. Russ. J. Genet. 2016; 52, 405-8.

A Baghizadeh, M Bahaaddini, MR Mohamadabadi and N Askari. Allelic Variations in Exon 2 of Caprine MHC Class II DRB3 Gene in Raeini Cashmere goat. Am. J. Agric. Environ. Sci. 2009; 6, 454-9.

M Moghadaszadeh, MR Mohammadabadi and AK Esmailizadeh. Association of exon 2 of BMP15 gene with the litter size in the Raini Cashmere goat. Genetics in the 3rd Millennium 2015; 13, 4062-7.

MN Ruzina, TA Shtyfurko, MR Mohammadabadi, OB Gendzhieva, T Tsedev and GE Sulimova. Polymorphism of the BOLA-DRB3 gene in the Mongolian, Kalmyk, and Yakut cattle breeds. Russ. J. Genet. 2010; 46, 456-63.

MR Mohammadabadi, N Askari, A Baghizadeh and AK Esmailizadeh. A directed search around caprine candidate loci provided evidence for microsatellites linkage to growth and Cashmere yield in Rayini goats. Small Rumin. Res. 2009; 81, 146-51.

B Soufy, MR Mohammadabadi, K Shojaeyan, A Baghizadeh, S Ferasaty, N Askari and O Dayani. Evaluation of myostatin gene polymorphism in Sanjabi sheep by PCR-RFLP method. Anim. Sci. Res. 2009; 19, 81-9.

A Mousavizadeh, MR Mohammadabadi, A Torabi, MR Nassiry, H Ghiasi and AK Esmailizadeh. Genetic polymorphism at the growth hormone locus in Iranian talli goats by Polymerase Chain Reaction-Single Strand Conformation Polymorphism (PCR-SSCP). Iran J. Biotech. 2009; 7, 51-3.

XY Lan, H Chen, CY Pan, LJ Ming, CZ Lei, LS Hua, CL Zhang and SR Hu. Polymorphism in growth hormone gene and its association with production traits in goats. J. Appl. Anim. Res. 2007; 32, 55-60.

MR Mohammadabadi, A Torabi, M Tahmourespoor, A Baghizadeh, AK Esmailizadeh and A Mohammadi. Analysis of bovine growth hormone gene polymorphism of local and Holstein cattle breeds in Kerman province of Iran using polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP). Afr. J. Biotech. 2010; 9, 6848-52.

P Schlee, R Graml, E Schallenberger, D Schams, O Rottmann, A OlbrichBludau and F Pirchner. Growth hormone and Insulin-like growth factor І concentrations in bull of various growth hormone genotypes. Theor. Appl. Genet. 1994; 88, 497-503.

A Valinsky, M Shani and E Gootwine. Restriction fragment length polymorphism in sheep at the growth hormone locus is the result of variation in gene number. Anim. Biotech. 1990; 1, 135-44.

Y Yamano, K Oyabayashi, M Okuno, M Yato, N Kioka, E Manabe, H Hashi, H Sakai, T Komano, K Utsumi and A Iritani. Cloning and sequencing of cdna that encodes goat growth hormone. 1988, 228, 301-4.

M Yato, Y Yamano, K Oyabayashi, M Okuno, N Kioka, E Manabe, H Hashi, H Sakai, T Komano, K Utsumi, K Utsumi and A Iritani. Nucleotide sequence of the growth hormone gene cdna from goat Tokara. Nucleic Acids Res. 1988; 16, 3578.

N Kioka, E Manabe, M Abe, H Hashi, M Yato, M Okuno, Y Yamano, H Sakai, T Komano, K Utsumi and A Iritani. Cloning and sequencing of goat growth hormone gene. Agric. Biol. Chem. 1989; 53, 1583-7.

HM Zhang, DR Brown, SK DeNise and RL Ax. Nucleotide sequence determination of a bovine somatotropin allele. Anim. Genet. 1992; 23, 578.

MA Meybodi. 1993, The Estimate Genetic Parameters for some Economic Traits in Raieni Cashmere Goats. MSC Thesis, Ferdowsi University, Mashhad, Iran.

E Malveiro, M Pereira, PX Marques, I Santos, CC Belo, R Renaville and AC Cravador. Polymorphisms at the five exons of the growth hormone gene in the algarvia goat: Possible association with milk traits. Small Rumin. Res. 2001; 41, 163-70.

PX Marques, M Pereira, MR Marques, IC Santos, CC Belo, R Renaville and A Cravador. Association of milk traits with SSCP polymorphisms at the growth hormone gene in the Serrana goat. Small Rumin. Res. 2003; 50, 177-85.

A Lagziel, E Lipkin and M Soller. Association between sscp haplotypes at the bovine growth hormone gene and milk protein percentage. Genetics 1996; 142, 945-51.

Ch Zhang, Y Liu, K Huang, W Zeng, D Xu, Q Wen and L Yang. The association of two single nucleotide polymorphisms (SNPs) in growth hormone (GH) gene with litter size and superovulation response in goat-breeds. Genet. Mol. Biol. 2011; 34, 49-55.

PP Singh, SS Tomar, MS Thakur and A Kumar. Polymorphism and association of growth hormone gene with growth traits in Sirohi and Barbari breeds of goat. Vet. World 2015; 8, 382-7.

N Askari, MR Mohammadabadi, MR Nassiry, A Baghizadeh and J Fayazi. Study of genetic diversity of Raeini Cashmere goat based on microsatellite markers. J. Agric. Sci. 2009; 18, 155-61.

N Askari, A Baghizadeh and MR Mohammadabadi. Analysis of the genetic structure of Iranian indigenous Raeni Cashmere goat populations using microsatellite markers. Biotechnology 2008; 2, 1-4.

N Askari, A Baghizadeh and MR Mohammadabadi. Study of genetic diversity in four populations of Raeini Cashmere goat using ISSR markers. Modern Genet. 2010; 5, 49-56.

MN Hassani, M Asadi Fozi, AK Esmailizadeh and MR Mohammadabadi. A genetic analysis of growth traits in Raieni Cashmere goat using multivariate animal model. Iran. J. Anim. Sci. 2010; 41, 323-9.

MR Mohammadabadi. Relationships of IGFBP-3 gene polymorphism with Cashmere traits in Raini Cashmere goat. Modern Genet. 2012; 7, 115-20.

F Tohidi nezhad, MR Mohammadabadi, AK Esmailizadeh and AN Noori. A Comparison of different levels of Rheb gene expression in different tissues of Raini Cashmir goat. J. Agric. Biotech. 2015; 6, 35-50.

SA Miller, DD Dykes and HF Polesky. A simple sating out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988; 16, 12-5.

GH Hua, SL Chen, JN Yu, KL Cai, CJ Wu, QL Li, CY Zhang, AX Liang, L Hana, LY Geng, Z Shen, DQ Xu and LG Yang. Polymorphism of the growth hormone gene and its association with growth traits in Boer goat bucks. Meat Sci. 2009; 81, 391-5.

FC Yeh, RC Yang and T Boyle. PopGene, Microsoft Windows based Freeware for Population Genetic Analysis. Release 131, University of Alberta, Canada, 1999.

AR Glimur, BR Cullis and R Thompson. ASReml User Guide. NSW Department of Industry and Investment, VSN International, Hemel Hempstead, UK.

G Wiener, GJ Lee and JA Woolliams. Effects of rapid inbreeding and of crossing inbred lines on the growth of linear body dimensions of sheep. Anim. Prod. 1992; 55, 101-4.

A Yakubu, AE Salako and AR Abdullah. Varimax rotated principal component analysis of the zoometrical traits of Uda sheep. Arch. Zootec. 2011; 60, 813-6.

I Boujenane and AE Hazzab. Genetic parameter for direct and mater effect on body weight of Draa goat. Small Rumin. Res. 2008; 69, 149-56.

Z Chungyan, Y Ligu and S Zhang. Variance components and genetic parameters for weight and size at birth in Boer goat. Livest. Prod. Sci. 2008; 115, 73-9.

A Bharathidhasan, R Narayanan, P Gopu, A Subramanian, R Prabakaran and R Rajendran. Effect of nongenetic factors on birth weight, weaning weight and preweaning gain of Barbari goat. J. Vet. Anim. Sci. 2009; 5, 99-103.

HN Hermiz, JE Alkass, AA Hobi and MK Asofi. Genetic and phenotypic parameters of body weights in Iraqi local goat and their crosses with damascus. J. Duhok Univ. 2009; 12, 189-94.

BJ Restall, and WA Pattie. The inheritance of Cashmere in Australian goats. 2 Genetic parameters and breeding value. Livest. Prod. Sci. 1989; 21, 251-61.

S Walkden-Brown, B Sunduimijid, B Olayemi, J Van Der Werf and A Ruvinsky. Breeding Fiber Goat for Resistance to Worm Infections. Rural Industries Research and Development Corporation, University of New England, Armidale, Australia, 2008, p. 70-87.

D Allain and J Roguet. Genetic and nongenetic factors influencing mohair production traits within the national selection scheme of Angora goats in France. Livest. Prod. Sci. 2003; 82, 129-37.

MAE Meybodi. The Estimate Genetic Parameters for some Economic Traits in Raieni Cashmere Goats. Ferdowsi University of Mashhad, Mashhad, Iran, 1993.

EM Nejad and MA Fozi. Effect of environmental factors on fleece weight of Raeini Cashmere goats. J. Anim. Sci. Res. 2012; 22, 1-9.

M Yamaki, GSS Correa, MA Silva, L Barbosa and RA Torres. Evaluation of quail carcass traits using principal component analysis. In: Proceedings of the 8th World Congress on Genetics Applied to Livestock Production, Brazil, 2006.

F Pariacote, L Ruiz, DCD Ascencao, C Borges and X Pimentel. Morphological traits of Venezuelan Creole goat, Arch. Latinoamericanos Prod. Anim. 2004; 12, S1.

VAC Santos and JMT Azevedo. The use of multivariate analysis to characterize carcass and meat quality of goat kids protected by PGI “Cabrito de Barroso”. Livest. Sci. 2008; 116, 70-81.

A Yakubu, AE Salako and GI Ikhide. Comparative multivariate analysis of biometric traits of West African Dwarf and Red Sokoto goats. Trop. Anim. Health Prod. 2011; 43, 561-6.

C Deng, R Ma, X Yue, X Lan, H Chen and C Lei. Association of IGF-1 gene polymorphism with milk yield and body size in Chinese dairy goats. Genet. Mol. Biol. 2010; 33, 266-70.

CX Zhang, W Zhang, H Luo, WM Gao and Z Jia. A new single nucleotide polymorphism in the igf-1 gene and its association with growth trait in the Nan Jiang Huang goat. Asian Aust. J. Anim. Sci. 2008; 21, 1073-9.

SHG Wickramaratne, BR Ulmek, SP Dixit, S Kumar and MK Vyas. Use of growth hormone gene polymorphism in selecting Osmanabadi and Sangamneri goats. Trop. Agric. Res. 2010; 21, 398-411.

YMA Saleha, FM Karima, MS Lamiaa and SA Ekram. Genetic polymorphism of five genes associated with growth traits in goat. Afr. J. Biotech. 2012; 2, 14738-48.

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Published

2018-10-13

How to Cite

GOOKI, F. G., MOHAMMADABADI, M., FOZI, M. A., & SOFLAEI, M. (2018). Association of Biometric Traits with Growth Hormone Gene Diversity in Raini Cashmere Goats. Walailak Journal of Science and Technology (WJST), 16(7), 499–508. https://doi.org/10.48048/wjst.2019.3791

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Research Article